A SAS® MACRO TO ADDRESS PK TIMING VARIABLES ISSUES

This paper discusses and lists a SAS® macro which addresses the challenge of evaluating timing variables and chronological sequencing for collected PK sampling and patient dosing data when sample and dose dates and times are not always recorded correctly on, or are omitted from, the case report form input. Examples of such datasets are PKS, POPPK, and NONMEM.
This macro is intended for use with the input data in CDISC format for a single dose per visit, with a single pre-dose sample and following post dose samples.

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